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LIN LAB

Medical College
of Wisconsin

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We study mechanical signaling in the heart in heart attacks and muscular dystrophy. Muscular dystrophy is commonly associated with severe muscle weakness and the loss of the ability to walk. However, muscular dystrophy patients ultimately die from heart failure. Conversely, a common feature for heart attack patients is exercise intolerance. Therefore, we consider both the heart and muscle in our studies.

Our Research

Our lab applies spatial transcriptomics, animal models of heart disease, single cardio-myocyte biomechanics, in silico drug discovery, nanoparticle drug delivery, and human stem cell engineering platforms to enable testing and screening of exciting new therapies to treat heart diseases and beyond.

High Throughput Stem Cell Modeling
Duchenne muscular dystrophy
TRPC6 inhibitors and Drug Discovery
Cardiomyocyte Biomechanics
Spatial Transcriptomics of Inflammatory Signaling
Platinum Stimulator Plates

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We're hiring!

T32 Postdoc Fellow Position Available

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